Phosphopantetheine
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| Phosphopantetheine | |
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| Identifiers | |
| CAS number | [2226-71-3] |
| PubChem | |
| MeSH | |
| Properties | |
| Molecular formula | C11H23N2O7PS |
| Molar mass | 358.349 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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4'-Phosphopantetheine is an essential prosthetic group of acyl carrier protein (ACP) and peptidyl carrier proteins (PCP) and aryl carrier proteins (ArCP) derived from Coenzyme A.
[edit] Functions
Phosphopantetheine fulfils two demands.
- Firstly, the intermediates remain covalently linked to the synthases (or synthetases) in an energy-rich thiol ester linkage.
- Secondly, the flexibility and length of phosphopantetheine chain (approximately 2 nm) allows the covalently tethered intermediates to have access to spatially distinct enzyme active sites.
[edit] See also
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