Phosphatidylethanolamine binding protein 1

From Wikipedia, the free encyclopedia

PDB rendering based on 1a44.

Available structures: 1a44, 1b7a, 1bd9, 1beh

Identifiers

Symbol(s)

PEBP1; PBP; HCNP; PEBP; RKIP

External IDs

OMIM: 604591 MGI: 1344408 HomoloGene: 37637

Gene ontology
Molecular Function:	• nucleotide binding • serine-type endopeptidase inhibitor activity • ATP binding • lipid binding • phosphatidylethanolamine binding

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002567 (mRNA)
NP_002558 (protein)

NM_018858 (mRNA)
NP_061346 (protein)

Location

Chr 12: 117.06 - 117.07 Mb

Chr 5: 117.54 - 117.55 Mb

Pubmed search

[1]

[2]

Phosphatidylethanolamine binding protein 1, also known as PEBP1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PEBP1 phosphatidylethanolamine binding protein 1.

[edit] Further reading

Schoentgen F, Jollès P (1995). "From structure to function: possible biological roles of a new widespread protein family binding hydrophobic ligands and displaying a nucleotide binding site.". FEBS Lett. 369 (1): 22-6. PMID 7641877.
Ojika K, Mitake S, Tohdoh N, et al. (2000). "Hippocampal cholinergic neurostimulating peptides (HCNP).". Prog. Neurobiol. 60 (1): 37-83. PMID 10622376.
Odabaei G, Chatterjee D, Jazirehi AR, et al. (2004). "Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis.". Adv. Cancer Res. 91: 169-200. doi:10.1016/S0065-230X(04)91005-6. PMID 15327891.
Hochstrasser DF, Frutiger S, Paquet N, et al. (1993). "Human liver protein map: a reference database established by microsequencing and gel comparison.". Electrophoresis 13 (12): 992-1001. PMID 1286669.
Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317-20. PMID 1602151.
Tohdoh N, Tojo S, Agui H, Ojika K (1995). "Sequence homology of rat and human HCNP precursor proteins, bovine phosphatidylethanolamine-binding protein and rat 23-kDa protein associated with the opioid-binding protein.". Brain Res. Mol. Brain Res. 30 (2): 381-4. PMID 7637590.
Seddiqi N, Bollengier F, Alliel PM, et al. (1995). "Amino acid sequence of the Homo sapiens brain 21-23-kDa protein (neuropolypeptide h3), comparison with its counterparts from Rattus norvegicus and Bos taurus species, and expression of its mRNA in different tissues.". J. Mol. Evol. 39 (6): 655-60. PMID 7807553.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Hori N, Chae KS, Murakawa K, et al. (1994). "A human cDNA sequence homologue of bovine phosphatidylethanolamine-binding protein.". Gene 140 (2): 293-4. PMID 8144042.
Moore C, Perry AC, Love S, Hall L (1996). "Sequence analysis and immunolocalisation of phosphatidylethanolamine binding protein (PBP) in human brain tissue.". Brain Res. Mol. Brain Res. 37 (1-2): 74-8. PMID 8738137.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Banfield MJ, Barker JJ, Perry AC, Brady RL (1998). "Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction.". Structure 6 (10): 1245-54. PMID 9782050.
Yeung K, Seitz T, Li S, et al. (1999). "Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP.". Nature 401 (6749): 173-7. doi:10.1038/43686. PMID 10490027.
Yeung K, Janosch P, McFerran B, et al. (2000). "Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein.". Mol. Cell. Biol. 20 (9): 3079-85. PMID 10757792.
Hengst U, Albrecht H, Hess D, Monard D (2001). "The phosphatidylethanolamine-binding protein is the prototype of a novel family of serine protease inhibitors.". J. Biol. Chem. 276 (1): 535-40. doi:10.1074/jbc.M002524200. PMID 11034991.
Yeung KC, Rose DW, Dhillon AS, et al. (2001). "Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation.". Mol. Cell. Biol. 21 (21): 7207-17. doi:10.1128/MCB.21.21.7207-7217.2001. PMID 11585904.
Maki M, Matsukawa N, Yuasa H, et al. (2002). "Decreased expression of hippocampal cholinergic neurostimulating peptide precursor protein mRNA in the hippocampus in Alzheimer disease.". J. Neuropathol. Exp. Neurol. 61 (2): 176-85. PMID 11853019.
Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.". Genome Res. 12 (11): 1773-84. doi:10.1101/gr.406902. PMID 12421765.