Phosphatidylcholine-dolichol O-acyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a phosphatidylcholine---dolichol O-acyltransferase (EC 2.3.1.83) is an enzyme that catalyzes the chemical reaction

3-sn-phosphatidylcholine + dolichol 1-acyl-sn-glycero-3-phosphocholine + acyldolichol

Thus, the two substrates of this enzyme are 3-sn-phosphatidylcholine and dolichol, whereas its two products are 1-acyl-sn-glycero-3-phosphocholine and acyldolichol.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is 3-sn-phosphatidylcholine:dolichol O-acyltransferase.

[edit] References

• IUBMB entry for 2.3.1.83
• BRENDA references for 2.3.1.83 (Recommended.)
• PubMed references for 2.3.1.83
• PubMed Central references for 2.3.1.83
• Google Scholar references for 2.3.1.83
• Keenan RW, Kruczek ME (1976). "The esterification of dolichol by rat liver microsomes". Biochemistry. 15: 1586–91. doi:10.1021/bi00652a032. PMID 4095. 
• Radominska-Pyrek A, Chojnacki T, Zulczyk W (1979). "Acyl esters of polyprenols: specificity of microsomal transacylase for polyprenols of different chain length and saturation". Acta. Biochim. Pol. 26: 125–34. PMID 506613. 

[edit] External links

The CAS registry number for this enzyme class is 9012-30-0.

• IUBMB entry for 2.3.1.83

• KEGG entry for 2.3.1.83

• BRENDA entry for 2.3.1.83

• NiceZyme view of 2.3.1.83

• EC2PDB: PDB structures for 2.3.1.83

• PRIAM entry for 2.3.1.83

• PUMA2 entry for 2.3.1.83

• IntEnz: Integrated Enzyme entry for 2.3.1.83

• MetaCyc entry for 2.3.1.83

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047199: phosphatidylcholine-dolichol O-acyltransferase

• AMIGO entry for GO code 0047199: phosphatidylcholine-dolichol O-acyltransferase