Phenylserine aldolase

From Wikipedia, the free encyclopedia

In enzymology, a phenylserine aldolase (EC 4.1.2.26) is an enzyme that catalyzes the chemical reaction

L-threo-3-phenylserine glycine + benzaldehyde

Hence, this enzyme has one substrate, L-threo-3-phenylserine, and two products, glycine and benzaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming). This enzyme is also called L-threo-3-phenylserine benzaldehyde-lyase. It employs one cofactor, pyridoxal phosphate.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1V72.

[edit] References

• IUBMB entry for 4.1.2.26
• BRENDA references for 4.1.2.26 (Recommended.)
• PubMed references for 4.1.2.26
• PubMed Central references for 4.1.2.26
• Google Scholar references for 4.1.2.26
• BRUNS FH, FIEDLER L (1958). "Enzymatic cleavage and synthesis of L-threo-beta-phenylserine and L-erythro-beta-Phenyldrine". Nature. 181: 1533–4. doi:10.1038/1811533a0. PMID 13566053. 

[edit] External links

The CAS registry number for this enzyme class is 37290-60-1.

• IUBMB entry for 4.1.2.26

• KEGG entry for 4.1.2.26

• BRENDA entry for 4.1.2.26

• NiceZyme view of 4.1.2.26

• EC2PDB: PDB structures for 4.1.2.26

• PRIAM entry for 4.1.2.26

• PUMA2 entry for 4.1.2.26

• IntEnz: Integrated Enzyme entry for 4.1.2.26

• MetaCyc entry for 4.1.2.26

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050179: phenylserine aldolase

• AMIGO entry for GO code 0050179: phenylserine aldolase