Portal:Pharmacy and Pharmacology/Medicinal chemistry
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| Main page | Pharmaceutics | Medicinal chemistry | Pharmacology and Medications | Pharmacognosy and Medical Herbs |
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing, synthesizing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for the purpose of medicinal products.
Medicinal chemistry is a highly interdisciplinary science combining organic chemistry with biochemistry, computational chemistry, pharmacology, pharmacognosy, molecular biology, statistics, and physical chemistry.
- Medicinal chemistry
- Journal of Medicinal Chemistry
- Journal of Molecular Biology
- ADME studies
- SAR = Structure-Activity relationship
- Qsar = Quantitative structure-activity relationship
- Pharmacophore
- Natural product
- Drug discovery
- Drug design
- Enzyme inhibitor
- Pharmacodynamics
- Pharmacokinetics
- Bioavailability
- Mechanism of action
- Combinatorial chemistry
- High-throughput screening
- Molecular modelling
- Molecular mechanics & Molecular dynamics
- Force field
- Toxicokinetics
- Semisynthesis
- Chemical synthesis
- Polar surface area
- Partition coefficient
- LogD-Distribution coefficient
