PGPEP1

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Pyroglutamyl-peptidase I
Identifiers
Symbol(s) PGPEP1; PGP; FLJ20208; MGC10812; PGP-I; PGPI; Pcp
External IDs OMIM: 610694 MGI: 1913772 HomoloGene: 9793
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 54858 66522
Ensembl ENSG00000130517 ENSMUSG00000056204
Uniprot Q9NXJ5 Q9ESW8
Refseq NM_017712 (mRNA)
NP_060182 (protein)		 NM_023217 (mRNA)
NP_075706 (protein)
Location Chr 19: 18.31 - 18.34 Mb Chr 8: 73.58 - 73.59 Mb
Pubmed search [1] [2]

Pyroglutamyl-peptidase I, also known as PGPEP1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: PGPEP1 pyroglutamyl-peptidase I.

[edit] Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Valdivia A, Irazusta J, Fernández D, et al. (2005). "Pyroglutamyl peptidase I and prolyl endopeptidase in human semen: increased activity in necrozoospermia.". Regul. Pept. 122 (2): 79-84. doi:10.1016/j.regpep.2004.05.005. PMID 15380924. 
  • Minderman H, O'Loughlin KL, Pendyala L, Baer MR (2004). "VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.". Clin. Cancer Res. 10 (5): 1826-34. PMID 15014037. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Dando PM, Fortunato M, Strand GB, et al. (2003). "Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme.". Protein Expr. Purif. 28 (1): 111-9. PMID 12651114. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gil J, Larrinaga G, Meana JJ, et al. (2002). "Regional and subcellular distribution of soluble aminopeptidase in the human and the rat brain: a comparative study.". Neuropeptides 35 (5-6): 276-84. doi:10.1054/npep.2001.0870. PMID 12030812. 
  • Charli JL, Mendez M, Vargas MA, et al. (1990). "Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices.". Neuropeptides 14 (3): 191-6. PMID 2575716. 
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