Talk:Peroxisome proliferator-activated receptor
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[edit] human ppar-delta activation
where can i get ppar-delta activating medicaments? —The preceding unsigned comment was added by 84.61.15.154 (talk) 12:50, 31 March 2007 (UTC).
[edit] Muraglitazar
We should perhaps quote Steven Nissen's destruction of muraglitazar as an antidiabetic. Obviously, we still know too little about PPAR to predict firmly what modulation will do to bone and coronary artery. JFW | T@lk 21:23, 27 November 2007 (UTC)
- RE: Muraglitazar: I presume you mean this? Nissen SE, Wolski K, Topol EJ (2005). "Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus". JAMA 294 (20): 2581–6. doi:. PMID 16239637. Boghog2 (talk) 21:47, 27 November 2007 (UTC)
- RE: PPAR modulators effect on bone: this looks sobering: Takada I, Suzawa M, Matsumoto K, Kato S (2007). "Suppression of PPAR-γ transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts". Ann N Y Acad Sci. doi:. PMID 17656564. Boghog2 (talk) 21:47, 27 November 2007 (UTC)
