Pennsylvania Route 388
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| PA Route 388 |
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| Length: | 8 mi (13 km) | ||||||||||||
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| Formed: | 1928 | ||||||||||||
| north end: | PA 168 in East Brook. | ||||||||||||
| south end: | PA 65 in Energy. | ||||||||||||
| Counties: | Lawrence | ||||||||||||
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Pennsylvania Route 388 is a north-south state highway in Lawrence County, Pennsylvania, United States, located in Western Pennsylvania. It travels eight miles between PA 168 in East Brook and PA 65 in Energy.

