PDLIM3

From Wikipedia, the free encyclopedia

PDZ and LIM domain 3

PDB rendering based on 1v5l.

Available structures: 1v5l

Identifiers

Symbol(s)

PDLIM3; ALP; DKFZp686L0362

External IDs

OMIM: 605889 HomoloGene: 8710

Gene ontology
Molecular Function:	• cytoskeletal protein binding • zinc ion binding • structural constituent of muscle • metal ion binding
Cellular Component:	• actin cytoskeleton
Biological Process:	• actin filament organization • heart development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

n/a

Refseq

NM_014476 (mRNA)
NP_055291 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 4: 186.66 - 186.69 Mb

n/a

Pubmed search

[1]

n/a

PDZ and LIM domain 3, also known as PDLIM3, is a human gene.^[1]

[edit] References

^ Entrez Gene: PDLIM3 PDZ and LIM domain 3.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Piétu G, Alibert O, Guichard V, et al. (1996). "Novel gene transcripts preferentially expressed in human muscles revealed by quantitative hybridization of a high density cDNA array.". Genome Res. 6 (6): 492–503. PMID 8828038.
Xia H, Winokur ST, Kuo WL, et al. (1997). "Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs.". J. Cell Biol. 139 (2): 507–15. PMID 9334352.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Bouju S, Piétu G, Le Cunff M, et al. (1999). "Exclusion of muscle specific actinin-associated LIM protein (ALP) gene from 4q35 facioscapulohumeral muscular dystrophy (FSHD) candidate genes.". Neuromuscul. Disord. 9 (1): 3–10. PMID 10063829.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Klaavuniemi T, Kelloniemi A, Ylänne J (2004). "The ZASP-like motif in actinin-associated LIM protein is required for interaction with the alpha-actinin rod and for targeting to the muscle Z-line.". J. Biol. Chem. 279 (25): 26402–10. doi:10.1074/jbc.M401871200. PMID 15084604.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Brown AK, O'Connor PJ, Roberts TE, et al. (2006). "Ultrasonography for rheumatologists: the development of specific competency based educational outcomes.". Ann. Rheum. Dis. 65 (5): 629–36. doi:10.1136/ard.2005.039974. PMID 16192291.
Arola AM, Sanchez X, Murphy RT, et al. (2007). "Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy.". Mol. Genet. Metab. 90 (4): 435–40. doi:10.1016/j.ymgme.2006.12.008. PMID 17254821.