PCTK3

From Wikipedia, the free encyclopedia

PCTAIRE protein kinase 3

Identifiers

PCTK3; PCTAIRE; PCTAIRE3

External IDs

OMIM: 169190 MGI: 97518 HomoloGene: 1949

Gene ontology
Molecular Function:	• nucleotide binding • protein kinase activity • protein serine/threonine kinase activity • signal transducer activity • ATP binding • transferase activity
Cellular Component:	• cellular_component
Biological Process:	• protein amino acid phosphorylation • signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002596 (mRNA)
NP_002587 (protein)

NM_008795 (mRNA)
NP_032821 (protein)

Location

Chr 1: 203.74 - 203.77 Mb

Chr 1: 133.94 - 133.97 Mb

Pubmed search

[1]

[2]

PCTAIRE protein kinase 3, also known as PCTK3, is a human gene.^[1]

[edit] References

^ Entrez Gene: PCTK3 PCTAIRE protein kinase 3.

[edit] Further reading

Okuda T, Cleveland JL, Downing JR (1992). "PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family.". Oncogene 7 (11): 2249–58. PMID 1437147.
Meyerson M, Enders GH, Wu CL, et al. (1992). "A family of human cdc2-related protein kinases.". EMBO J. 11 (8): 2909–17. PMID 1639063.
Okuda T, Valentine VA, Shapiro DN, Downing JR (1994). "Cloning of genomic loci and chromosomal localization of the human PCTAIRE-1 and -3 protein kinase genes.". Genomics 21 (1): 217–21. doi:10.1006/geno.1994.1245. PMID 8088790.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Herskovits AZ, Davies P (2004). "Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain.". Gene 328: 59–67. doi:10.1016/j.gene.2003.12.011. PMID 15019984.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Palmer KJ, Konkel JE, Stephens DJ (2005). "PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport.". J. Cell. Sci. 118 (Pt 17): 3839–47. doi:10.1242/jcs.02496. PMID 16091426.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Herskovits AZ, Davies P (2006). "The regulation of tau phosphorylation by PCTAIRE 3: implications for the pathogenesis of Alzheimer's disease.". Neurobiol. Dis. 23 (2): 398–408. doi:10.1016/j.nbd.2006.04.004. PMID 16766195.
Wissing J, Jänsch L, Nimtz M, et al. (2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.". Mol. Cell Proteomics 6 (3): 537–47. doi:10.1074/mcp.T600062-MCP200. PMID 17192257.