PCBD2

From Wikipedia, the free encyclopedia

Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2

Identifiers

PCBD2; DCOH2; DCOHM

External IDs

OMIM: 609836 MGI: 1919812 HomoloGene: 49987

Gene ontology
Molecular Function:	• phenylalanine 4-monooxygenase activity • protein binding • 4-alpha-hydroxytetrahydrobiopterin dehydratase activity • lyase activity
Cellular Component:	• cellular_component • nucleus
Biological Process:	• tetrahydrobiopterin biosynthetic process • positive regulation of transcription, DNA-dependent • protein homotetramerization • protein heterooligomerization

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_032151 (mRNA)
NP_115527 (protein)

NM_028281 (mRNA)
NP_082557 (protein)

Location

Chr 5: 134.27 - 134.32 Mb

Chr 13: 55.74 - 55.79 Mb

Pubmed search

[1]

[2]

Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2, also known as PCBD2, is a human gene.^[1]

[edit] References

^ Entrez Gene: PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs.". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMID 11591653.
Lim S, Jin K, Friedman E (2002). "Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.". J. Biol. Chem. 277 (28): 25040–6. doi:10.1074/jbc.M203257200. PMID 11980910.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Arias JM, Murbartián J, Perez-Reyes E (2003). "Cloning of a novel one-repeat calcium channel-like gene.". Biochem. Biophys. Res. Commun. 303 (1): 31–6. PMID 12646162.
Rose RB, Pullen KE, Bayle JH, et al. (2004). "Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2.". Biochemistry 43 (23): 7345–55. doi:10.1021/bi049620t. PMID 15182178.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Schaaf CP, Benzing J, Schmitt T, et al. (2005). "Novel interaction partners of the TPR/MET tyrosine kinase.". FASEB J. 19 (2): 267–9. doi:10.1096/fj.04-1558fje. PMID 15546961.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.