Padimate A

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Padimate A

IUPAC name	4-dimethylaminobenzoic acid isopentyl ester
Other names	isoamyl dimethyl PABA Escalol 506
Identifiers
CAS number	[21245-01-2]
PubChem	88836
SMILES	CC(C)CCOC(=O)C1=CC=C(C=C1)N(C)C
Properties
Molecular formula	C₁₄H₂₁NO₂
Molar mass	235.322
Melting point	<25 °C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Padimate A is an organic compound that is an ingredient in some sunscreens. It is an ester derivative of PABA. This aromatic chemical absorbs ultraviolet rays thereby preventing sunburn. However, it's chemical structure and behaviour is similar to an industrial free radical generator.^[1] In Europe this chemical was withdrawn in 1989 for unstated reasons.^[1] In the US it was never approved for use in sunscreens.

[edit] Photobiology

The photobiological properties of padimate O and padimate A resemble that of Michler's ketone. These compounds have been shown to increase the lethal effects of UV-radiation on cells.^[1] This photochemistry is relevant to the sunscreen controversy.

[edit] See also

Padimate O, a related suncreen ingredient

[edit] References

^ ^a ^b ^c Knowland, John; McKenzie, Edward A.; McHugh, Peter J.; Cridland, Nigel A. (1993). "Sunlight-induced mutagenicity of a common sunscreen ingredient.". FEBS Letters 324(3): 309-313.