Talk:P2X receptor

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[edit] Suggestions for additions and improvements

Subcellular (talk) 16:20, 7 April 2008 (UTC) Gene info boxes interfere with page format (all the edit tabs are displaced).

Given there are now pages for each receptor subunit, the gene infoboxes area little redundent here aren't they? This page should not contain such specific information, which should only be on the specific gene pages. For example like nAChRs WW9066 (talk) 21:36, 18 April 2008 (UTC)
OK, I agree that including 7 protein boxes in one article was a little excessive. I have removed the protein boxes, but have converted the receptor subtype list into a table so that at least the chromosomal location of each of the receptors gene is retained. I hope that this is an improvement. Boghog2 (talk) 14:30, 19 April 2008 (UTC)
Thanks for that, I like the new table. I would have made the changes myself (I'm slowly getting the hang of editing pages myself) - though I probably wouldn't have such a good job. WW9066 (talk) 19:44, 19 April 2008 (UTC)

I appreciate that this should probably be on the specific pages (though they are very quiet currently, and this is a kind've parent page to all seven), but should those pages be named after the gene name or the protein name? I think at least I shall put some redirects in. Is there a wikipedia convention for this in Biological articles? Presumably the article should cover both the gene and protein, as it would be total over-kill to have separate articles for the gene and protein.WW9066 (talk) 19:44, 19 April 2008 (UTC)

With very few exceptions, each gene and the corresponding protein encoded by that gene has one and only one WP article whose subject matter comprises both the gene and the protein. The reason I included both the P2X receptor and corresponding HUGO gene name in the table was primarily to inform the reader that the names of the gene and protein differ slightly. Cheers. Boghog2 (talk) 22:52, 19 April 2008 (UTC)

[edit] Discussion regarding changes

Subcellular (talk) 16:20, 7 April 2008 (UTC) I removed the suramin structure because it seemed a little unnecessary and out of place. Any objections?

None at all. Any suggestions for a picture to put on this page? Structure of ATP is all I can think of, but it's not all that relevant. WW9066 (talk) 12:21, 8 April 2008 (UTC)
Subcellular (talk) 14:14, 21 April 2008 (UTC) There's no crystal structure available (yet), so other than a schematic of the basic P2X subunit topology, there isn't really much to illustrate. Given that an Acid-Sensing Ion Channel was recently resolved (another trimer), I'm tempted to just wait and see. Speaking of ASIC, somebody should really put something on that page!

[edit] P2XLR1?

Isn't this more commonly known as P2X6? I know it doesn't form homomeric receptors, but within the field it's more commonly known as P2X6. What is the consensus?WW9066 (talk) 21:24, 18 April 2008 (UTC)

Apparently the official HUGO gene name was until recently P2XLR1 but has now changed to P2X6. Therefore I have made the corresponding changes in the text of this article. Cheers. Boghog2 (talk) 21:52, 18 April 2008 (UTC)