Oxalomalate lyase

From Wikipedia, the free encyclopedia

In enzymology, an oxalomalate lyase (EC 4.1.3.13) is an enzyme that catalyzes the chemical reaction

3-oxalomalate oxaloacetate + glyoxylate

Hence, this enzyme has one substrate, 3-oxalomalate, and two products, oxaloacetate and glyoxylate.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-oxalomalate glyoxylate-lyase (oxaloacetate-forming). This enzyme is also called 3-oxalomalate glyoxylate-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

[edit] References

• IUBMB entry for 4.1.3.13
• BRENDA references for 4.1.3.13 (Recommended.)
• PubMed references for 4.1.3.13
• PubMed Central references for 4.1.3.13
• Google Scholar references for 4.1.3.13
• Sekizawa Y, Maragoudakis ME, King TE, Cheldelin VH (1966). "Glutamate biosynthesis in an organism lacking a Krebs tricarboxylic acid cycle. V. Isolation of alpha-hydroxy-gamma-ketoglutarate (HKG) in Acetobacter suboxydans". Biochemistry. 5: 2392–8. doi:10.1021/bi00871a032. PMID 6005666. 

[edit] External links

The CAS registry number for this enzyme class is 37290-63-4.

• IUBMB entry for 4.1.3.13

• KEGG entry for 4.1.3.13

• BRENDA entry for 4.1.3.13

• NiceZyme view of 4.1.3.13

• EC2PDB: PDB structures for 4.1.3.13

• PRIAM entry for 4.1.3.13

• PUMA2 entry for 4.1.3.13

• IntEnz: Integrated Enzyme entry for 4.1.3.13

• MetaCyc entry for 4.1.3.13

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050204: oxalomalate lyase

• AMIGO entry for GO code 0050204: oxalomalate lyase