OTUD7B

From Wikipedia, the free encyclopedia

OTU domain containing 7B

Identifiers

OTUD7B; CEZANNE; ZA20D1

External IDs

Gene ontology
Molecular Function:	• DNA binding • ubiquitin thiolesterase activity • protein binding • cysteine-type peptidase activity • zinc ion binding • metal ion binding
Cellular Component:	• nucleus • cytoplasm
Biological Process:	• protein deubiquitination • negative regulation of I-kappaB kinase/NF-kappaB cascade

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_020205 (mRNA)
NP_064590 (protein)

NM_001025613 (mRNA)
NP_001020784 (protein)

Location

Chr 1: 148.18 - 148.25 Mb

Chr 3: 96.19 - 96.25 Mb

Pubmed search

[1]

[2]

OTU domain containing 7B, also known as OTUD7B, is a human gene.^[1]

[edit] References

^ Entrez Gene: OTUD7B OTU domain containing 7B.

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711-8. doi:10.1101/gr.2435604. PMID 15342556.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Evans PC, Ovaa H, Hamon M, et al. (2004). "Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity.". Biochem. J. 378 (Pt 3): 727-34. doi:10.1042/BJ20031377. PMID 14748687.
Evans PC, Smith TS, Lai MJ, et al. (2003). "A novel type of deubiquitinating enzyme.". J. Biol. Chem. 278 (25): 23180-6. doi:10.1074/jbc.M301863200. PMID 12682062.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Evans PC, Taylor ER, Coadwell J, et al. (2001). "Isolation and characterization of two novel A20-like proteins.". Biochem. J. 357 (Pt 3): 617-23. PMID 11463333.
Heyninck K, Beyaert R (1999). "The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6.". FEBS Lett. 442 (2-3): 147-50. PMID 9928991.