One Big Holiday

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One Big Holiday is a song by American rock band My Morning Jacket. It has become their signature song, and is their most requested song at concerts. They performed it at the music festival Bonnaroo for four straight years, starting in 2003. It was featured on their third studio album It Still Moves and their 2006 live album, Okonokos.

It is also notable for its guitar riff heard in the first minute of the song and the guitar solos at the end of the song, as well as highlighting Jim James voice.

The 2007 film "The Lookout" features this song in the beginning credits. The medical series, "House", also features this song at the beginning of episode 6, season 4. The 2006 film Stick It also features the song in its soundtrack.