OMG (gene)

From Wikipedia, the free encyclopedia

Oligodendrocyte myelin glycoprotein

Identifiers

OMG; OMGP

External IDs

OMIM: 164345 MGI: 106586 HomoloGene: 36099

Gene ontology
Molecular Function:	• protein binding • GPI anchor binding
Cellular Component:	• membrane fraction • integral to plasma membrane • membrane
Biological Process:	• cell adhesion

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002544 (mRNA)
NP_002535 (protein)

NM_019409 (mRNA)
NP_062282 (protein)

Location

Chr 17: 26.65 - 26.65 Mb

Chr 11: 79.32 - 79.32 Mb

Pubmed search

[1]

[2]

Oligodendrocyte myelin glycoprotein, also known as OMG, is a human gene.^[1]

[edit] References

^ Entrez Gene: OMG oligodendrocyte myelin glycoprotein.

[edit] Further reading

Mikol DD, Gulcher JR, Stefansson K (1990). "The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate.". J. Cell Biol. 110 (2): 471–9. PMID 1688857.
Viskochil D, Cawthon R, O'Connell P, et al. (1991). "The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene.". Mol. Cell. Biol. 11 (2): 906–12. PMID 1899288.
Mikol DD, Alexakos MJ, Bayley CA, et al. (1991). "Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein.". J. Cell Biol. 111 (6 Pt 1): 2673–9. PMID 2277079.
Mikol DD, Stefansson K (1988). "A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes.". J. Cell Biol. 106 (4): 1273–9. PMID 3283151.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Mikol DD, Rongnoparut P, Allwardt BA, et al. (1993). "The oligodendrocyte-myelin glycoprotein of mouse: primary structure and gene structure.". Genomics 17 (3): 604–10. doi:10.1006/geno.1993.1379. PMID 8244377.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Wang KC, Koprivica V, Kim JA, et al. (2002). "Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth.". Nature 417 (6892): 941–4. doi:10.1038/nature00867. PMID 12068310.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Vourc'h P, Moreau T, Arbion F, et al. (2003). "Oligodendrocyte myelin glycoprotein growth inhibition function requires its conserved leucine-rich repeat domain, not its glycosylphosphatidyl-inositol anchor.". J. Neurochem. 85 (4): 889–97. PMID 12716421.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Venturin M, Moncini S, Villa V, et al. (2007). "Mutations and novel polymorphisms in coding regions and UTRs of CDK5R1 and OMG genes in patients with non-syndromic mental retardation.". Neurogenetics 7 (1): 59–66. doi:10.1007/s10048-005-0026-9. PMID 16425041.
Douglas J, Cilliers D, Coleman K, et al. (2007). "Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth.". Nat. Genet. 39 (8): 963–5. doi:10.1038/ng2083. PMID 17632510.