Oligopeptide-transporting ATPase

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In enzymology, an oligopeptide-transporting ATPase (EC 3.6.3.23) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + oligopeptideout $\rightleftharpoons$ ADP + phosphate + oligopeptidein

The 3 substrates of this enzyme are ATP, H₂O, and oligopeptide, whereas its 3 products are ADP, phosphate, and oligopeptide.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (oligopeptide-importing). This enzyme is also called oligopeptide permease.

[edit] References

IUBMB entry for 3.6.3.23
BRENDA references for 3.6.3.23 (Recommended.)
PubMed references for 3.6.3.23
PubMed Central references for 3.6.3.23
Google Scholar references for 3.6.3.23
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Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977.
Griffiths JK and Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998".
Pearce SR, Mimmack ML, Gallagher MP, Gileadi U, Hyde SC, Higgins CF (1992). "Membrane topology of the integral membrane components, OppB and OppC, of the oligopeptide permease of Salmonella typhimurium". Mol. Microbiol. 6: 47–57. doi:10.1111/j.1365-2958.1992.tb00836.x. PMID 1738314.