OLFM1

From Wikipedia, the free encyclopedia

Olfactomedin 1

Identifiers

OLFM1; AMY; NOE1; NOELIN1; OlfA

External IDs

OMIM: 605366 MGI: 1860437 HomoloGene: 8612

Gene ontology
Molecular Function:	• protein binding • latrotoxin receptor activity
Cellular Component:	• extracellular space • endoplasmic reticulum • membrane
Biological Process:	• multicellular organismal development • nervous system development • protein oligomerization

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006334 (mRNA)
NP_006325 (protein)

NM_001038612 (mRNA)
NP_001033701 (protein)

Location

Chr 9: 137.11 - 137.15 Mb

Chr 2: 28.02 - 28.05 Mb

Pubmed search

[1]

[2]

Olfactomedin 1, also known as OLFM1, is a human gene.^[1]

This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.^[1]

[edit] References

^ ^a ^b Entrez Gene: OLFM1 olfactomedin 1.

[edit] Further reading

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yokoyama M, Nishi Y, Yoshii J, et al. (1997). "Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles.". DNA Res. 3 (5): 311–20. PMID 9039501.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Camargo LM, Collura V, Rain JC, et al. (2007). "Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.". Mol. Psychiatry 12 (1): 74–86. doi:10.1038/sj.mp.4001880. PMID 17043677.