Oleoylethanolamide
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| Oleoylethanolamide | |
|---|---|
 |
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| IUPAC name | (Z)-N-(2-hydroxyethyl)octadec-9-enamide |
| Identifiers | |
| CAS number | [111-58-0] |
| PubChem | |
| SMILES | CCCCCCCC\C=C/CCCCCCCC(=O)NCCO |
| Properties | |
| Molecular formula | C20H39NO2 |
| Molar mass | 325.53 |
| Appearance | White solid |
| Melting point |
59-60°C |
| Solubility in water | soluble in ethanol and DMSO |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Oleoylethanolamide is an endogenous PPAR-α agonist. It is a naturally-occurring lipid derivative that regulates feeding and body weight.[1][2] It is structurally related to the putative endocannabinoid anandamide.
[edit] References
- ^ Gaetani S, Oveisi F, Piomelli D (2003). "Modulation of meal pattern in the rat by the anorexic lipid mediator oleoylethanolamide". Neuropsychopharmacology 28 (7): 1311–6. PMID 12700681.
- ^ Lo Verme J, Gaetani S, Fu J, Oveisi F, Burton K, Piomelli D (2005). "Regulation of food intake by oleoylethanolamide". Cell. Mol. Life Sci. 62 (6): 708–16. doi:. PMID 15770421.
[edit] External links
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