NUP160

From Wikipedia, the free encyclopedia

Nucleoporin 160kDa

Identifiers

NUP160; MGC150678; MGC150679

External IDs

OMIM: 607614 MGI: 1926227 HomoloGene: 32509

Gene ontology
Molecular Function:	• nucleocytoplasmic transporter activity • protein binding
Cellular Component:	• nucleus • nuclear pore
Biological Process:	• mRNA export from nucleus • transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_015231 (mRNA)
NP_056046 (protein)

NM_021512 (mRNA)
NP_067487 (protein)

Location

Chr 11: 47.76 - 47.83 Mb

Chr 2: 90.48 - 90.54 Mb

Pubmed search

[1]

[2]

Nucleoporin 160kDa, also known as NUP160, is a human gene.^[1]

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: NUP160 nucleoporin 160kDa.

[edit] Further reading

Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 3 (1): 17-24. PMID 8724849.
Belgareh N, Rabut G, Baï SW, et al. (2001). "An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.". J. Cell Biol. 154 (6): 1147-60. doi:10.1083/jcb.200101081. PMID 11564755.
Vasu S, Shah S, Orjalo A, et al. (2001). "Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.". J. Cell Biol. 155 (3): 339-54. doi:10.1083/jcb.200108007. PMID 11684705.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Loïodice I, Alves A, Rabut G, et al. (2005). "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.". Mol. Biol. Cell 15 (7): 3333-44. doi:10.1091/mbc.E03-12-0878. PMID 15146057.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315-23. doi:10.1101/gr.2122004. PMID 15231747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391-6. doi:10.1073/pnas.0507066103. PMID 16565220.
Orjalo AV, Arnaoutov A, Shen Z, et al. (2006). "The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.". Mol. Biol. Cell 17 (9): 3806-18. doi:10.1091/mbc.E05-11-1061. PMID 16807356.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
Glavy JS, Krutchinsky AN, Cristea IM, et al. (2007). "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 3811-6. doi:10.1073/pnas.0700058104. PMID 17360435.
Zuccolo M, Alves A, Galy V, et al. (2007). "The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.". EMBO J. 26 (7): 1853-64. doi:10.1038/sj.emboj.7601642. PMID 17363900.