NEUROG1

From Wikipedia, the free encyclopedia

Neurogenin 1

Identifiers

NEUROG1; AKA; Math4C; NEUROD3; ngn1

External IDs

OMIM: 601726 MGI: 107754 HomoloGene: 4490

Gene ontology
Molecular Function:	• transcription factor activity
Cellular Component:	• nucleus
Biological Process:	• regulation of transcription from RNA polymerase II promoter • multicellular organismal development • nervous system development • neuron differentiation • positive regulation of exit from mitosis • inner ear morphogenesis • cell fate commitment

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006161 (mRNA)
NP_006152 (protein)

NM_010896 (mRNA)
NP_035026 (protein)

Location

Chr 5: 134.9 - 134.9 Mb

Chr 13: 56.26 - 56.26 Mb

Pubmed search

[1]

[2]

Neurogenin 1, also known as NEUROG1, is a human gene.^[1]

[edit] References

^ Entrez Gene: NEUROG1 neurogenin 1.

[edit] Further reading

McCormick MB, Tamimi RM, Snider L, et al. (1996). "NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family.". Mol. Cell. Biol. 16 (10): 5792–800. PMID 8816493.
Tamimi RM, Steingrimsson E, Montgomery-Dyer K, et al. (1997). "NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively.". Genomics 40 (2): 355–7. doi:10.1006/geno.1996.4578. PMID 9119405.
Sun Y, Nadal-Vicens M, Misono S, et al. (2001). "Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms.". Cell 104 (3): 365–76. PMID 11239394.
Franklin A, Kao A, Tapscott S, Unis A (2002). "NeuroD homologue expression during cortical development in the human brain.". J. Child Neurol. 16 (11): 849–53. PMID 11732772.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Kim S, Ghil SH, Kim SS, et al. (2004). "Overexpression of neurogenin1 induces neurite outgrowth in F11 neuroblastoma cells.". Exp. Mol. Med. 34 (6): 469–75. PMID 12526089.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Fanous AH, Chen X, Wang X, et al. (2007). "Association between the 5q31.1 gene neurogenin1 and schizophrenia.". Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (2): 207–14. doi:10.1002/ajmg.b.30423. PMID 17044100.