Nervonic acid
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| Nervonic acid[1] | |
|---|---|
 |
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| IUPAC name | (Z)-Tetracos-15-enoic acid |
| Other names | cis-15-Tetracosenoic acid 24:1 cis, delta 9 or 24:1 omega 9 |
| Identifiers | |
| CAS number | [506-37-6] |
| PubChem | |
| SMILES | CCCCCCCC\C=C/CCCCCCCCCCCCCC(=O)O |
| Properties | |
| Molecular formula | C24H46O2 |
| Molar mass | 366.62 g/mol |
| Melting point |
42-43 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Nervonic acid is a monounsaturated omega-9 fatty acid. Nervonic acid has been identified as important in the biosynthesis of nerve cell myelin.[2] It is found in the sphingolipids of white matter in human brain.
Nervonic acid is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.[3]
[edit] Notes
- ^ Nervonic acid at Sigma-Aldrich
- ^ US Patent 6664406, Nervonic acid derivatives, their preparation and use
- ^ WO/1996/005740, Nervonic Acid Compositions
[edit] Additional references
- Appelqvist (1976) Lipids in Cruciferae. In: Vaughan JG, Macleod AJ (Eds), The biology and the Chemistry of Cruciferae. Academic Press, London, UK, pp. 221-277.
- Sargent JR, Coupland K, Wilson R (1994). Nervonic Acid and Demyelinating Disease. Medical Hypothesese 42, pp. 237-242.
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