Image:Neprilysin 1r1h.png

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[edit] Summary

Description

The structure of neprilysin, a zinc metalloprotease involved in the metabolism of extracellular regulatory peptides such as the enkephalins and substance P. Neprilysin in neural tissue is the major protease degrading amyloid beta, a peptide fragment whose abnormal misfolding and aggregation is associated with Alzheimer's disease. The gray sphere represents a zinc atom; the green structure is a zinc-chelating enzyme inhibitor.

Source

Self-created from PDB ID 1R1H using PyMol

Date

7 Mar 2007

Author

Opabinia regalis

Permission
(Reusing this image)

GFDL


[edit] Licensing

I, the copyright holder of this work, hereby publish it under the following license:
GNU head Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation license, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled "GNU Free Documentation license".

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File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeDimensionsUserComment
current02:41, 8 March 20071,086×814 (501 KB)Opabinia regalis (wrong version, forgot to crop)
02:39, 8 March 20071,700×1,118 (530 KB)Opabinia regalis ({{Information |Description=The structure of neprilysin, a zinc metalloprotease involved in the metabolism of extracellular regulatory peptides such as the enkephalins and substance P. Neprilysin in neural tissue is the major protease degrading amyloid bet)
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