NDUFB8

From Wikipedia, the free encyclopedia

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa

Identifiers

NDUFB8; ASHI; CI-ASHI

External IDs

OMIM: 602140 MGI: 1914514 HomoloGene: 3668

Gene ontology
Molecular Function:	• NADH dehydrogenase activity • NADH dehydrogenase (ubiquinone) activity • oxidoreductase activity
Cellular Component:	• membrane fraction • mitochondrion • mitochondrial inner membrane • endoplasmic reticulum
Biological Process:	• electron transport • mitochondrial electron transport, NADH to ubiquinone

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005004 (mRNA)
NP_004995 (protein)

NM_026061 (mRNA)
NP_080337 (protein)

Location

Chr 10: 102.27 - 102.28 Mb

Chr 19: 44.6 - 44.61 Mb

Pubmed search

[1]

[2]

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa, also known as NDUFB8, is a human gene.^[1]

[edit] References

^ Entrez Gene: NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Dunbar DR, Shibasaki Y, Dobbie L, et al. (1997). "In situ hybridisation mapping of genomic clones for five human respiratory chain complex I genes.". Cytogenet. Cell Genet. 78 (1): 21-4. PMID 9345899.
Emahazion T, Brookes AJ (1998). "Mapping of the NDUFA2, NDUFA6, NDUFA7, NDUFB8, and NDUFS8 electron transport chain genes by intron based radiation hybrid mapping.". Cytogenet. Cell Genet. 82 (1-2): 114. PMID 9763676.
Loeffen JL, Triepels RH, van den Heuvel LP, et al. (1999). "cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.". Biochem. Biophys. Res. Commun. 253 (2): 415-22. doi:10.1006/bbrc.1998.9786. PMID 9878551.
Emahazion T, Jobs M, Howell WM, et al. (1999). "Identification of 167 polymorphisms in 88 genes from candidate neurodegeneration pathways.". Gene 238 (2): 315-24. PMID 10570959.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546-60. PMID 11042152.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287-92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ma J, Dempsey AA, Stamatiou D, et al. (2007). "Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.". Atherosclerosis 191 (1): 63-72. doi:10.1016/j.atherosclerosis.2006.05.032. PMID 16806233.
Hsieh SM, Maguire DJ, Lintell NA, et al. (2007). "PTEN and NDUFB8 aberrations in cervical cancer tissue.". Adv. Exp. Med. Biol. 599: 31-6. PMID 17727244.