Talk:Nadolol

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Beta-2 receptors in bronchiolar smooth muscle mediate BRONCHODILATION, increasing bronchiolar lumen diameter and relieving asthma symptoms; blocking these will potentiate asthma. Vascular smooth muscle contain beta-2 receptors that mediate muscle relaxation (VASODILATION); blocking these will cause vasoconstriction.

The Macula Densa cells of the Distal Convoluted Tubules (DCT) have beta-1 receptors that respond to either NaCl concentration within the tubule (also relates to flow rate) as well as SNS innervation (NE). These Macula Densa cells release prostaglandins that impact abutting JG cells of the efferent arteriole, causing renin release.

[edit] typo?

I'm not a medic/biologist but it seems to me that there's a typo in "should be avoided in asthma patients in preference of a beta-1 blocker such as propanolol", as propranolol is a nonselective blocker. Probably metoprolol or other beta-1 blocker should be mentioned. Please correct if you are sure.