N6-hydroxylysine O-acetyltransferase

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In enzymology, a N6-hydroxylysine O-acetyltransferase (EC 2.3.1.102) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + N₆-hydroxy-L-lysine $\rightleftharpoons$ CoA + N₆-acetyl-N₆-hydroxy-L-lysine

Thus, the two substrates of this enzyme are acetyl-CoA and N6-hydroxy-L-lysine, whereas its two products are CoA and N6-acetyl-N6-hydroxy-L-lysine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase. Other names in common use include N6-hydroxylysine:acetyl CoA N6-transacetylase, N6-hydroxylysine acetylase, and acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase. This enzyme participates in lysine degradation.

[edit] References

IUBMB entry for 2.3.1.102
BRENDA references for 2.3.1.102 (Recommended.)
PubMed references for 2.3.1.102
PubMed Central references for 2.3.1.102
Google Scholar references for 2.3.1.102
Coy M, Paw BH, Bindereif A, Neilands JB (1986). "Isolation and properties of N epsilon-hydroxylysine:acetyl coenzyme A N epsilon-transacetylase from Escherichia coli pABN11". Biochemistry. 25: 2485–9. PMID 3521734.
de Lorenzo V, Bindereif A, Paw BH, Neilands JB (1986). "Aerobactin biosynthesis and transport genes of plasmid ColV-K30 in Escherichia coli K-12". J. Bacteriol. 165: 570–8. PMID 2935523.