N-Oxalylglycine
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| N-Oxalylglycine | |
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| IUPAC name | N-oxalylglycine |
| Other names | NOG; [(carboxymethyl)amino](oxo)acetic acid |
| Identifiers | |
| CAS number | [5262-39-5] |
| Properties | |
| Molecular formula | C4H5NO5 |
| Molar mass | 147.1 |
| Appearance | colourless solid |
| Solubility in water | water, dmso |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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N-Oxalylglycine is the organic compound with the formula HO2CC(O)NHCH2CO2H. This colourless solid is used as an inhibitor of α-ketoglutarate-dependent enzymes.[1] It is isosteric with α-ketoglutaric acid. Such enzymes are pervasive and, for example, are required for the synthesis of 4-hydroxyproline.
[edit] References
- ^ Hausinger, R. P."Fe(II)/α-ketoglutarate-dependent hydroxylases and related enzymes" Critical Reviews of Biochemical Molecular Biology 2004, 39: pp 21-68.DOI: 10.1080/10409230490440541
