N-Methylmorpholine N-oxide
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| N-Methylmorpholine N-oxide | |
|---|---|
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| Identifiers | |
| CAS number | [7529-22-8] |
| SMILES | [O-][N+]1(C)CCOCC1 |
| Properties | |
| Molecular formula | C5H11NO2 |
| Molar mass | 117.15 g/mol |
| Melting point |
180 - 184 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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N-Methylmorpholine-N-oxide or NMO is an organic compound. This heterocyclic amine oxide and morpholine derivative is used in organic chemistry as a co-oxidant and sacrificial catalyst in oxidation reactions for instance in osmium tetroxide oxidations and the Sharpless asymmetric dihydroxylation or oxidations with TPAP. NMO is commercially supplied both as a monohydrate C5H11NO2.H2O and as the anhydrous compound. NMO is used as a solvent for Lyocell manufacturing.
Oxidation of an alkene with osmium tetroxide (0.06 eq.) and NMO (1.2 eq.)in acetone/water 5:1 RT 12 hrs.[1]
[edit] References
- ^ Preparation of 3H-Pyrrolo[2,3-c]isoquinolines and 3H-Pyrrolo[2,3-c][2,6]- and 3H-Pyrrolo[2,3-c][1,7]-naphthyridines U. Narasimha Rao, Xuemei Han and Edward R. Biehl Arkivoc 2002 (x) 61-66 Online Article
