N-hydroxyarylamine O-acetyltransferase
From Wikipedia, the free encyclopedia
In enzymology, a N-hydroxyarylamine O-acetyltransferase (EC 2.3.1.118) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + an N-hydroxyarylamine
CoA + an N-acetoxyarylamine
Thus, the two substrates of this enzyme are acetyl-CoA and N-hydroxyarylamine, whereas its two products are CoA and N-acetoxyarylamine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N-hydroxyarylamine O-acetyltransferase. Other names in common use include arylhydroxamate N,O-acetyltransferase, arylamine N-acetyltransferase, and N-hydroxy-2-aminofluorene-O-acetyltransferase.
Contents |
[edit] Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1E2T.
[edit] References
- IUBMB entry for 2.3.1.118
- BRENDA references for 2.3.1.118 (Recommended.)
- PubMed references for 2.3.1.118
- PubMed Central references for 2.3.1.118
- Google Scholar references for 2.3.1.118
- Saito K, Shinohara A, Kamataki T, Kato R (Tokyo). "N-hydroxyarylamine O-acetyltransferase in hamster liver: identity with arylhydroxamic acid N,O-acetyltransferase and arylamine N-acetyltransferase". J. Biochem.: 1689–97. PMID 3745141.
[edit] External links
-
- The CAS registry number for this enzyme class is 100984-92-7.

