N-carbamoyl-D-amino acid hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a N-carbamoyl-D-amino acid hydrolase (EC 3.5.1.77) is an enzyme that catalyzes the chemical reaction

N-carbamoyl-D-amino acid + H₂O D-amino acid + NH₃ + CO₂

Thus, the two substrates of this enzyme are N-carbamoyl-D-amino acid and H₂O, whereas its 3 products are D-amino acid, NH₃, and CO₂.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is '.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1ERZ, 1UF4, 1UF5, 1UF7, 1UF8, 2GGK, and 2GGL.

[edit] References

• IUBMB entry for 3.5.1.77
• BRENDA references for 3.5.1.77 (Recommended.)
• PubMed references for 3.5.1.77
• PubMed Central references for 3.5.1.77
• Google Scholar references for 3.5.1.77
• Ogawa J, Shimizu S, Yamada H (1993). "N-carbamoyl-D-amino acid amidohydrolase from Comamonas sp. E222c purification and characterization". Eur. J. Biochem. 212: 685–91. PMID 8462543. 

[edit] External links

The CAS registry number for this enzyme class is 71768-08-6.

• IUBMB entry for 3.5.1.77

• KEGG entry for 3.5.1.77

• BRENDA entry for 3.5.1.77

• NiceZyme view of 3.5.1.77

• EC2PDB: PDB structures for 3.5.1.77

• PRIAM entry for 3.5.1.77

• PUMA2 entry for 3.5.1.77

• IntEnz: Integrated Enzyme entry for 3.5.1.77

• MetaCyc entry for 3.5.1.77

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047417: N-carbamoyl-D-amino acid hydrolase

• AMIGO entry for GO code 0047417: N-carbamoyl-D-amino acid hydrolase