N-Acetylglutamic acid
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| N-Acetylglutamic acid | |
|---|---|
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| IUPAC name | (2S)-2-Acetamidopentanedioic acid |
| Other names | Acetylglutamic acid, N-Acetylglutamic acid, N-Acetyl-L-glutamic acid, N-Acetyl-Glu, Ac-Glu-OH, NAcGlu |
| Identifiers | |
| CAS number | [1188-37-0] |
| PubChem | |
| SMILES | OC(=O)CC[C@H](NC(=O)C)C(=O)O |
| InChI | 1/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10) 11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13) |
| Properties | |
| Molecular formula | C7H11NO5 |
| Molar mass | 189.17 g/mol |
| Density | 1 g/cm3 |
| Melting point |
191 - 194 °C |
| Solubility in water | 36 g/l |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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N-Acetylglutamic acid (abbreviated NAcGlu) is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetylglutamate synthase. Arginine is the activator for this reaction.
The reverse reaction, hydrolysis of the acetyl group, is catalyzed by a specific hydrolase.
NAcGlu activates carbamoyl phosphate synthase in the urea cycle.
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