Mucinaminylserine mucinaminidase

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In enzymology, a mucinaminylserine mucinaminidase (EC 3.2.1.110) is an enzyme that catalyzes the chemical reaction

D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H₂O $\rightleftharpoons$ D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine

Thus, the two substrates of this enzyme are D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine and H₂O, whereas its two products are D-galactosyl-3-N-acetyl-beta-D-galactosamine and L-serine.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase. Other names in common use include endo-alpha-N-acetylgalactosaminidase, and endo-alpha-N-acetyl-D-galactosaminidase.

[edit] References

IUBMB entry for 3.2.1.110
BRENDA references for 3.2.1.110 (Recommended.)
PubMed references for 3.2.1.110
PubMed Central references for 3.2.1.110
Google Scholar references for 3.2.1.110
Bhavanandan VP, Umemoto J, Davidson EA (1976). "Characterization of an endo-alpha-N-acetyl galactosaminidase from Diplococcus pneumoniae". Biochem. Biophys. Res. Commun. 70: 738–45. PMID 7253.
Endo Y, Kobata A (Tokyo). "Partial purification and characterization of an endo-alpha-N-acetylgalactosaminidase from the culture of medium of Diplococcus pneumoniae". J. Biochem.: 1–8. PMID 9374.
Umemoto J, Bhavanandan VP, Davidson EA (1977). "Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae". J. Biol. Chem. 252: 8609–14. PMID 21877.