MUC3A

From Wikipedia, the free encyclopedia

Mucin 3A, cell surface associated

Identifiers

External IDs

Gene ontology
Molecular Function:	• extracellular matrix constituent, lubricant activity
Cellular Component:	• extracellular region
Biological Process:	• maintenance of gastrointestinal epithelium

Orthologs

Human

Mouse

Entrez

4584

n/a

Pubmed search

[1]

n/a

Mucin 3A, cell surface associated, also known as MUC3A, is a human gene.^[1]

[edit] References

^ Entrez Gene: MUC3A mucin 3A, cell surface associated.

[edit] Further reading

Fox MF, Lahbib F, Pratt W, et al. (1993). "Regional localization of the intestinal mucin gene MUC3 to chromosome 7q22.". Ann. Hum. Genet. 56 (Pt 4): 281–7. PMID 1362870.
Gum JR, Hicks JW, Swallow DM, et al. (1990). "Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.". Biochem. Biophys. Res. Commun. 171 (1): 407–15. PMID 2393399.
Gum JR, Ho JJ, Pratt WS, et al. (1997). "MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.". J. Biol. Chem. 272 (42): 26678–86. PMID 9334251.
"Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097–108. PMID 9847074.
Williams SJ, Munster DJ, Quin RJ, et al. (1999). "The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.". Biochem. Biophys. Res. Commun. 261 (1): 83–9. doi:10.1006/bbrc.1999.1001. PMID 10405327.
Crawley SC, Gum JR, Hicks JW, et al. (1999). "Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.". Biochem. Biophys. Res. Commun. 263 (3): 728–36. doi:10.1006/bbrc.1999.1466. PMID 10512748.
Pratt WS, Crawley S, Hicks J, et al. (2000). "Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.". Biochem. Biophys. Res. Commun. 275 (3): 916–23. doi:10.1006/bbrc.2000.3406. PMID 10973822.
Kyo K, Muto T, Nagawa H, et al. (2001). "Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.". J. Hum. Genet. 46 (1): 5–20. PMID 11289722.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Gum JR, Hicks JW, Crawley SC, et al. (2004). "Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.". J. Biol. Chem. 278 (49): 49600–9. doi:10.1074/jbc.M305769200. PMID 12958310.
Leroy X, Gouyer V, Ballereau C, et al. (2003). "Quantitative RT-PCR assay for MUC3 and VEGF mRNA in renal clear cell carcinoma: relationship with nuclear grade and prognosis.". Urology 62 (4): 771–5. PMID 14550470.