MPHOSPH1

From Wikipedia, the free encyclopedia

M-phase phosphoprotein 1

Identifiers

MPHOSPH1; MPP1; DKFZp434B0435; DKFZp434P0810; KRMP1; MPP-1

External IDs

OMIM: 605498 MGI: 2444576 HomoloGene: 9418

Gene ontology
Molecular Function:	• nucleotide binding • microtubule motor activity • ATP binding • ATPase activity • WW domain binding
Cellular Component:	• nucleus • nucleoplasm • nucleolus • centrosome • microtubule • microtubule associated complex
Biological Process:	• microtubule-based movement • cell cycle • cell cycle arrest • regulation of mitosis • cell division

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_016195 (mRNA)
NP_057279 (protein)

XM_193936 (mRNA)
XP_193936 (protein)

Location

Chr 10: 91.45 - 91.52 Mb

Chr 19: 34.99 - 35.04 Mb

Pubmed search

[1]

[2]

M-phase phosphoprotein 1, also known as MPHOSPH1, is a human gene.^[1]

[edit] References

^ Entrez Gene: MPHOSPH1 M-phase phosphoprotein 1.

[edit] Further reading

Westendorf JM, Rao PN, Gerace L (1994). "Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope.". Proc. Natl. Acad. Sci. U.S.A. 91 (2): 714–8. PMID 8290587.
Matsumoto-Taniura N, Pirollet F, Monroe R, et al. (1997). "Identification of novel M phase phosphoproteins by expression cloning.". Mol. Biol. Cell 7 (9): 1455–69. PMID 8885239.
Fritzler MJ, Kerfoot SM, Feasby TE, et al. (2000). "Autoantibodies from patients with idiopathic ataxia bind to M-phase phosphoprotein-1 (MPP1).". J. Investig. Med. 48 (1): 28–39. PMID 10695267.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Kamimoto T, Zama T, Aoki R, et al. (2001). "Identification of a novel kinesin-related protein, KRMP1, as a target for mitotic peptidyl-prolyl isomerase Pin1.". J. Biol. Chem. 276 (40): 37520–8. doi:10.1074/jbc.M106207200. PMID 11470801.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Abaza A, Soleilhac JM, Westendorf J, et al. (2003). "M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesis.". J. Biol. Chem. 278 (30): 27844–52. doi:10.1074/jbc.M304522200. PMID 12740395.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.