| 0 mile |
Begins within Glendive at the junction of Towne Street and old U.S. Route 10 going north |
47°06′22.40″N, 104°44′06.19″W |
| 1 mile |
Crosses Interstate 94 |
47°06′52.81″N, 104°44′09.29″W |
| 4 mile |
Highway 254 branches off to the west |
47°09′14.03″N, 104°42′18.31″W |
| 15 mile |
Passes by Intake |
47°18′05.40″N, 104°30′40.53″W |
| 33 mile |
Passes by Savage |
47°31′39.75″N, 104°18′28.96″W |
| 41 mile |
Passes by Crane |
47°34′33.17″N, 104°15′44.40″W |
| 49 mile |
Joins Highway 200 while Highway 23 branches off to the east |
47°41′02.91″N, 104°10′43.67″W |
| 52 mile |
leaves Highway 200 at Sidney |
47°43′46.86″N, 104°09′48.40″W |
| 69 mile |
Crosses Highway 201 |
47°51′58.48″N, 104°17′23.31″W |
| 90 mile |
Crosses U.S. Route 2 at Culbertson |
48°09′00.15″N, 104°30′59.40″W |
| 103 mile |
At Froid, Highway 344 branches off to the west and Highway 405 branches off to the east |
48°20′00.69″N, 104°29′48.29″W |
| 109 mile |
Highway 350 branches off to the west toward Homestead |
48°25′01.20″N, 104°29′49.25″W |
| 115 mile |
Crosses Highway 515 at Medicine Lake |
48°25′01.20″N, 104°29′49.25″W |
| 124 mile |
Crosses Highway 258 at Reserve |
48°36′22.70″N, 104°26′23.89″W |
| 129 mile |
Passes Antelope just before Highway 517 branches off to the east |
48°42′22.74″N, 104°27′21.31″W |
| 136 mile |
Joins Highway 5 to the west |
48°45′51.44″N, 104°31′16.00″W |
| 137 mile |
Enters Plentywood where it leaves Highway 5 |
48°46′44.41″N, 104°34′07.81″W |
| 157 mile |
Ends at the Saskatchewan border where it becomes Highway 6 |
49°00′00.00″N, 104°34′26.79″W |
