Monogalactosyldiacylglycerol synthase

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In enzymology, a monogalactosyldiacylglycerol synthase (EC 2.4.1.46) is an enzyme that catalyzes the chemical reaction

UDP-galactose + 1,2-diacyl-sn-glycerol $\rightleftharpoons$ UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol

Thus, the two substrates of this enzyme are UDP-galactose and 1,2-diacyl-sn-glycerol, whereas its two products are UDP and 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase. Other names in common use include uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase, UDP-galactose:diacylglycerol galactosyltransferase, MGDG synthase, UDP galactose-1,2-diacylglycerol galactosyltransferase, UDP-galactose-diacylglyceride galactosyltransferase, UDP-galactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase, 1beta-MGDG, and 1,2-diacylglycerol 3-beta-galactosyltransferase. This enzyme participates in glycerolipid metabolism.

[edit] References

IUBMB entry for 2.4.1.46
BRENDA references for 2.4.1.46 (Recommended.)
PubMed references for 2.4.1.46
PubMed Central references for 2.4.1.46
Google Scholar references for 2.4.1.46
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Benning C, Ohta H (2005). "Three enzyme systems for galactoglycerolipid biosynthesis are coordinately regulated in plants". J. Biol. Chem. 280: 2397–400. doi:10.1074/jbc.R400032200. PMID 15590685.