Monckeberg's arteriosclerosis
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| Monckeberg's arteriosclerosis Classification and external resources |
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| MeSH | D050380 |
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Monckeberg's arteriosclerosis, also called medial calcific sclerosis, is a form of arteriosclerosis or vessel hardening, where calcium deposits form in the middle layer of the walls of medium sized vessels (the tunica media). This Human medial calcification, Mönckeberg’s sclerosis, is common and occurs independently of atherosclerosis. It is more frequent in people over 50 years of age and diabetics. In advanced cases of Monckeberg's medial calcific sclerosis, vessels may become rigid and lose their distensibility. It is associated with trophic foot ulceration and peripheral artery occlusive disease.
Its presence predicts risk of cardiovascular events and leg amputation in diabetic patients.
Mönckeberg's medial arteriosclerosis was diagnosed in 34 of 297 patients referred for pelvic radiography for a variety of reasons. It is strongly associated with metabolic bone disease, especially osteoporosis, whether induced by corticosteroids or arising spontaneously.
