MOGAT2

From Wikipedia, the free encyclopedia

Monoacylglycerol O-acyltransferase 2

Identifiers

MOGAT2; MGAT2; DGAT2L5; FLJ22644; MGC119183; MGC119184; MGC119185

External IDs

OMIM: 610270 MGI: 2663253 HomoloGene: 57020

Gene ontology
Molecular Function:	• 2-acylglycerol O-acyltransferase activity • acetyltransferase activity • transferase activity
Cellular Component:	• endoplasmic reticulum • membrane • integral to membrane
Biological Process:	• glycerol metabolic process • lipid metabolic process • diacylglycerol biosynthetic process • lipid biosynthetic process • triacylglycerol biosynthetic process • intestinal absorption

Orthologs

Human

Mouse

Refseq

NM_025098 (mRNA)
NP_079374 (protein)

NM_177448 (mRNA)
NP_803231 (protein)

Location

Chr 11: 75.11 - 75.12 Mb

Chr 7: 99.09 - 99.11 Mb

Pubmed search

[1]

[2]

Monoacylglycerol O-acyltransferase 2, also known as MOGAT2, is a human gene.^[1]

[edit] References

^ Entrez Gene: MOGAT2 monoacylglycerol O-acyltransferase 2.

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Winter A, van Eckeveld M, Bininda-Emonds OR, et al. (2004). "Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals.". Cytogenet. Genome Res. 102 (1-4): 42-7. doi:10.1159/000075723. PMID 14970677.
Cao J, Hawkins E, Brozinick J, et al. (2004). "A predominant role of acyl-CoA:monoacylglycerol acyltransferase-2 in dietary fat absorption implicated by tissue distribution, subcellular localization, and up-regulation by high fat diet.". J. Biol. Chem. 279 (18): 18878-86. doi:10.1074/jbc.M313272200. PMID 14966132.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Lockwood JF, Cao J, Burn P, Shi Y (2003). "Human intestinal monoacylglycerol acyltransferase: differential features in tissue expression and activity.". Am. J. Physiol. Endocrinol. Metab. 285 (5): E927-37. doi:10.1152/ajpendo.00179.2003. PMID 12824082.
Yen CL, Farese RV (2003). "MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine.". J. Biol. Chem. 278 (20): 18532-7. doi:10.1074/jbc.M301633200. PMID 12621063.
Cao J, Lockwood J, Burn P, Shi Y (2003). "Cloning and functional characterization of a mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2.". J. Biol. Chem. 278 (16): 13860-6. doi:10.1074/jbc.M300139200. PMID 12576479.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.