MOCOS

From Wikipedia, the free encyclopedia

Molybdenum cofactor sulfurase

Identifiers

MOCOS; MOS; HMCS; FLJ20733

External IDs

MGI: 1915841 HomoloGene: 9931

Gene ontology
Molecular Function:	• Mo-molybdopterin cofactor sulfurase activity • transaminase activity • lyase activity
Cellular Component:	• cellular_component
Biological Process:	• Mo-molybdopterin cofactor biosynthetic process • metabolic process • molybdopterin cofactor metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_017947 (mRNA)
NP_060417 (protein)

XM_484710 (mRNA)
XP_484710 (protein)

Location

Chr 18: 32.02 - 32.1 Mb

Chr 18: 24.79 - 24.84 Mb

Pubmed search

[1]

[2]

Molybdenum cofactor sulfurase, also known as MOCOS, is a human gene.^[1]

[edit] References

^ Entrez Gene: MOCOS molybdenum cofactor sulfurase.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Ichida K, Matsumura T, Sakuma R, et al. (2001). "Mutation of human molybdenum cofactor sulfurase gene is responsible for classical xanthinuria type II.". Biochem. Biophys. Res. Commun. 282 (5): 1194-200. doi:10.1006/bbrc.2001.4719. PMID 11302742.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Yamamoto T, Moriwaki Y, Takahashi S, et al. (2003). "Identification of a new point mutation in the human molybdenum cofactor sulferase gene that is responsible for xanthinuria type II.". Metab. Clin. Exp. 52 (11): 1501-4. PMID 14624414.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285-92. doi:10.1038/nbt1240. PMID 16964243.
Peretz H, Naamati MS, Levartovsky D, et al. (2007). "Identification and characterization of the first mutation (Arg776Cys) in the C-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS) associated with type II classical xanthinuria.". Mol. Genet. Metab. 91 (1): 23-9. doi:10.1016/j.ymgme.2007.02.005. PMID 17368066.