Mitochondrial protein-transporting ATPase

From Wikipedia, the free encyclopedia

In enzymology, a mitochondrial protein-transporting ATPase (EC 3.6.3.51) is an enzyme that catalyzes the chemical reaction

ATP + H₂O ADP + phosphate

Thus, the two substrates of this enzyme are ATP and H₂O, whereas its two products are ADP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (mitochondrial protein-importing).

[edit] References

• IUBMB entry for 3.6.3.51
• BRENDA references for 3.6.3.51 (Recommended.)
• PubMed references for 3.6.3.51
• PubMed Central references for 3.6.3.51
• Google Scholar references for 3.6.3.51
• Rassow J (1997). "Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane". EMBO. J. 16: 2205–16. doi:10.1093/emboj/16.9.2205. PMID 9171336. 
• Brunner M (1995). "The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system". Cell. 81: 1085–93. doi:10.1016/S0092-8674(05)80013-3. PMID 7600576. 
• Voos W, Martin H, Krimmer T, Pfanner N (1999). "Mechanisms of protein translocation into mitochondria". Biochim. Biophys. Acta. 1422: 235–54. PMID 10548718. 

[edit] External links

• IUBMB entry for 3.6.3.51

• KEGG entry for 3.6.3.51

• BRENDA entry for 3.6.3.51

• NiceZyme view of 3.6.3.51

• EC2PDB: PDB structures for 3.6.3.51

• PRIAM entry for 3.6.3.51

• PUMA2 entry for 3.6.3.51

• IntEnz: Integrated Enzyme entry for 3.6.3.51

• MetaCyc entry for 3.6.3.51

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008566: mitochondrial protein-transporting ATPase

• AMIGO entry for GO code 0008566: mitochondrial protein-transporting ATPase