MIRN21

From Wikipedia, the free encyclopedia


MicroRNA 21
Identifiers
Symbol(s) MIRN21; hsa-mir-21; miR-21
Orthologs
Human Mouse
Entrez 406991 n/a



Pubmed search [1] n/a

MicroRNA 21, also known as MIRN21, is a human gene.[1]


[edit] References

[edit] Further reading

  • Slaby O, Svoboda M, Fabian P, et al. (2008). "Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer.". Oncology 72 (5-6): 397-402. doi:10.1159/000113489. PMID 18196926. 
  • Meng F, Henson R, Wehbe-Janek H, et al. (2007). "MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.". Gastroenterology 133 (2): 647-58. doi:10.1053/j.gastro.2007.05.022. PMID 17681183. 
  • Sonkoly E, Wei T, Janson PC, et al. (2007). "MicroRNAs: novel regulators involved in the pathogenesis of Psoriasis?". PLoS ONE 2 (7): e610. doi:10.1371/journal.pone.0000610. PMID 17622355. 
  • Ji R, Cheng Y, Yue J, et al. (2007). "MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation.". Circ. Res. 100 (11): 1579-88. doi:10.1161/CIRCRESAHA.106.141986. PMID 17478730. 
  • Zhu S, Si ML, Wu H, Mo YY (2007). "MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).". J. Biol. Chem. 282 (19): 14328-36. doi:10.1074/jbc.M611393200. PMID 17363372. 
  • Chan JA, Krichevsky AM, Kosik KS (2005). "MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells.". Cancer Res. 65 (14): 6029-33. doi:10.1158/0008-5472.CAN-05-0137. PMID 16024602. 
  • Cai X, Hagedorn CH, Cullen BR (2004). "Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs.". RNA 10 (12): 1957-66. doi:10.1261/rna.7135204. PMID 15525708. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Mourelatos Z, Dostie J, Paushkin S, et al. (2002). "miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs.". Genes Dev. 16 (6): 720-8. doi:10.1101/gad.974702. PMID 11914277. 
  • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T (2001). "Identification of novel genes coding for small expressed RNAs.". Science 294 (5543): 853-8. doi:10.1126/science.1064921. PMID 11679670.