Minaprine

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Minaprine
Systematic (IUPAC) name
4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
Identifiers
CAS number 25905-77-5
ATC code  ?
PubChem 4199
Chemical data
Formula C17H22N4O 
Mol. mass 298.383 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Minaprine is an antidepressant drug which acts as a weak, short-acting monoamine oxidase inhibitor, acting mainly at the MAOA subtype.[1] It also has some acetylcholinesterase inhibitory activity.[2]



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[edit] References

  1. ^ Kan JP, Mouget-Goniot C, Worms P, Biziere K. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochemical Pharmacology. 1986 Mar 15;35(6):973-8. PMID 3954800
  2. ^ Contreras JM, Rival YM, Chayer S, Bourguignon JJ, Wermuth CG. Aminopyridazines as acetylcholinesterase inhibitors. Journal of Medicinal Chemistry. 1999 Feb 25;42(4):730-41. PMID 10052979
v • d • e
Psychoanaleptics: antidepressants (N06A)
MAOIs
Iproclozide • Iproniazid • Isocarboxazid • Minaprine • Nialamide • Pargyline • Phenelzine • Rasagiline • Selegiline • Toloxatone • Tranylcypromine
RIMAs: Befloxatone • Brofaromine • Cimoxatone • Beta-carbolines (Harmaline) • Moclobemide
RIs
SSREs
AAs