MIER1

From Wikipedia, the free encyclopedia

Mesoderm induction early response 1 homolog (Xenopus laevis)

Identifiers

MIER1; DKFZp781G0451; ER1; KIAA1610; MGC131940; MGC150640; MGC150641; MI-ER1; RP5-944N15.1; hMI-ER1

External IDs

MGI: 1918398 HomoloGene: 10861

Gene ontology
Molecular Function:	• DNA binding • signal transducer activity
Cellular Component:	• nucleus
Biological Process:	• transcription • regulation of transcription, DNA-dependent • positive regulation of I-kappaB kinase/NF-kappaB cascade

Orthologs

Human

Mouse

Refseq

NM_001077700 (mRNA)
NP_001071168 (protein)

NM_001039081 (mRNA)
NP_001034170 (protein)

Location

Chr 1: 67.16 - 67.23 Mb

Chr 4: 102.61 - 102.66 Mb

Pubmed search

[1]

[2]

Mesoderm induction early response 1 homolog (Xenopus laevis), also known as MIER1, is a human gene.^[1]

[edit] References

^ Entrez Gene: MIER1 mesoderm induction early response 1 homolog (Xenopus laevis).

[edit] Further reading

Paterno GD, Mercer FC, Chayter JJ, et al. (1999). "Molecular cloning of human er1 cDNA and its differential expression in breast tumours and tumour-derived cell lines.". Gene 222 (1): 77-82. PMID 9813250.
Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (4): 273-81. PMID 10997877.
Paterno GD, Ding Z, Lew YY, et al. (2003). "Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization.". Gene 295 (1): 79-88. PMID 12242014.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ding Z, Gillespie LL, Paterno GD (2003). "Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain.". Mol. Cell. Biol. 23 (1): 250-8. PMID 12482978.
Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.". Oncogene 22 (21): 3307-18. doi:10.1038/sj.onc.1206406. PMID 12761501.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Ding Z, Gillespie LL, Mercer FC, Paterno GD (2004). "The SANT domain of human MI-ER1 interacts with Sp1 to interfere with GC box recognition and repress transcription from its own promoter.". J. Biol. Chem. 279 (27): 28009-16. doi:10.1074/jbc.M403793200. PMID 15117948.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391-6. doi:10.1073/pnas.0507066103. PMID 16565220.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.