MFN2

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Mitofusin 2
Identifiers
Symbol(s)	MFN2; CMT2A; CMT2A2; CPRP1; HSG; KIAA0214; MARF
External IDs	OMIM: 608507 MGI: 2442230 HomoloGene: 8915
Gene ontology Molecular Function: • nucleotide binding • GTPase activity • GTP binding • hydrolase activity Cellular Component: • mitochondrion • mitochondrial outer membrane • cytosol • membrane • integral to membrane • outer membrane • intrinsic to mitochondrial outer membrane Biological Process: • protein targeting to mitochondrion • mitochondrial membrane organization and biogenesis • cell cycle arrest • mitochondrial fusion • negative regulation of Ras protein signal transduction • negative regulation of smooth muscle cell proliferation • mitochondrion localization
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	9927	170731
Ensembl	ENSG00000116688	ENSMUSG00000029020
Uniprot	O95140	Q3TEX7
Refseq	NM_014874 (mRNA) NP_055689 (protein)	XM_001002345 (mRNA) XP_001002345 (protein)
Location	Chr 1: 11.96 - 12 Mb	Chr 4: 146.72 - 146.75 Mb
Pubmed search	[1]	[2]

Mitofusin 2, also known as MFN2, is a human gene.

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein may play a role in the pathophysiology of obesity.^[1]

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[edit] Further reading