Methylamine-glutamate N-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a methylamine-glutamate N-methyltransferase (EC 2.1.1.21) is an enzyme that catalyzes the chemical reaction

methylamine + L-glutamate NH₃ + N-methyl-L-glutamate

Thus, the two substrates of this enzyme are methylamine and L-glutamate, whereas its two products are NH₃ and N-methyl-L-glutamate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is methylamine:L-glutamate N-methyltransferase. Other names in common use include N-methylglutamate synthase, and methylamine-glutamate methyltransferase. This enzyme participates in methane metabolism.

[edit] References

• IUBMB entry for 2.1.1.21
• BRENDA references for 2.1.1.21 (Recommended.)
• PubMed references for 2.1.1.21
• PubMed Central references for 2.1.1.21
• Google Scholar references for 2.1.1.21
• Shaw WV, Tsai L, Stadtman ER (1966). "The enzymatic synthesis of N-methylglutamic acid". J. Biol. Chem. 241: 935–45. PMID 5905132. 

[edit] External links

The CAS registry number for this enzyme class is 9045-32-3.

• IUBMB entry for 2.1.1.21

• KEGG entry for 2.1.1.21

• BRENDA entry for 2.1.1.21

• NiceZyme view of 2.1.1.21

• EC2PDB: PDB structures for 2.1.1.21

• PRIAM entry for 2.1.1.21

• PUMA2 entry for 2.1.1.21

• IntEnz: Integrated Enzyme entry for 2.1.1.21

• MetaCyc entry for 2.1.1.21

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047148: methylamine-glutamate N-methyltransferase

• AMIGO entry for GO code 0047148: methylamine-glutamate N-methyltransferase