METTL2B

From Wikipedia, the free encyclopedia


Methyltransferase like 2B
Identifiers
Symbol(s) METTL2B; FLJ11350; FLJ12760; METL; METTL2; METTL2A; PSENIP1
External IDs OMIM: 607846 HomoloGene88854
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 55798 n/a
Ensembl ENSG00000165055 n/a
Refseq NM_018396 (mRNA)
NP_060866 (protein)
n/a (mRNA)
n/a (protein)
Location Chr 7: 127.9 - 127.93 Mb n/a
Pubmed search [1] n/a

Methyltransferase like 2B, also known as METTL2B, is a human gene.[1]

This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.[1]

[edit] References

[edit] Further reading

  • Zody MC, Garber M, Adams DJ, et al. (2006). "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.". Nature 440 (7087): 1045-9. doi:10.1038/nature04689. PMID 16625196. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711-8. doi:10.1101/gr.2435604. PMID 15342556. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Zhang SX, Guo Y, Boulianne GL (2002). "Identification of a novel family of putative methyltransferases that interact with human and Drosophila presenilins.". Gene 280 (1-2): 135-44. PMID 11738826. 
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546-60. PMID 11042152.