Talk:Meprobamate

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[edit] Wrong chemical structure

The chemical structure of meprobamate is missing 2 methyl groups: CH2OCONH2 should replace OCONH2

A new structure has now been uploaded. Based on image at The Comparative Toxicogenomics Database--Colin 19:57, 20 December 2005 (UTC)

[edit] The Columbia Encyclopedia, Sixth Edition

I've noticed that almost the whole of this text can be found in The Columbia Encyclopedia (Copyright 2001-05 Columbia University Press). Therefore I've completely revised the text and included more research. I've decided to remove it from the category of anticonvulsants since it isn't licensed as such. Indeed it is used with caution in epilepsy (see British National Formulary 50: "May induce seizures"). --Colin 23:41, 20 December 2005 (UTC)

[edit] History

Inconsistency:

I'm an idiot, pardon my entering this in the wrong place, but I didn't see how to do it right.

The article claims that the compound was synthesized in 1950, but that a court case had found that 1948, it had generated a multi-million dollar number in sales. Someone please move my comment to the correct place, but also reconcile this error. —Preceding unsigned comment added by 75.71.253.204 (talk) 07:11, 17 October 2007 (UTC)

I have removed the Trivia section statement by an anonymous contributor from 69.121.68.125 on 4th December 2006 that meprobamate was the first drug used to treat high blood pressure. This is hardly credible for a drug introduced in the 1950s. Other antihypertensives available before it included reserpine (and herbal rauwolfia), the early thiazide diuretics such as chlorothiazide, the vasodilator hydralazine and the ganglion-blockers. NRPanikker (talk) 02:01, 29 December 2007 (UTC)