Melanocytic tumors of uncertain malignant potential
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Melanocytic tumors of uncertain malignant potential (MELTUMP) are melanocytic lesions in the dermis that cannot be classified by morphology as either benign naevi (moles) or malignant melanomas because the mass shows features of both.
Several lesion types may be classified as MELTUMPs: atypical Spitz naevi, dysplastic naevi, pigmented epithelioid melanocytoma, deep penetrating naevi, congenital neavi, cellular nodules in congenital naevi, possible naevoid melanomas, and cellular blue naevi.[1][2]
A related category of melanocytic proliferation is superficial atypical melanocytic proliferations of uncertain significance (SAMPUS), which includes junctional melanocytic proliferations and proliferations in the epidermis and papillary dermis that are not accompanied by tumorigenic cell mitosis.[1]
[edit] References
- ^ a b Elder, David E.; Xiaowei Xu (October 2004). "The approach to the patient with a difficult melanocytic lesion". Pathology 36 (5): 428. doi:.
- ^ Byrd, David R.; David E. Elder; James M. Grichnik; John M. Kirkwood; and Merrick I. Ross (2006-08-01). Melanoma Care Options (PDF) 6-8. Melanoma Care Coalition. Retrieved on 2007-02-27.
[edit] Further reading
- Murphy, George F. "Case 12: Melanocytic tumor of uncertain malignant potential (MELTUMP)", in Artur Zembowicz (ed): Cases in Dermatopathology: Common Problems in Diagnosis of Pigmented Lesions. Los Gatos, California: Knowledge Books and Software, 73–80. ISBN 1741620880. Retrieved on 2007-02-27.
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