MAP4K1

From Wikipedia, the free encyclopedia

Mitogen-activated protein kinase kinase kinase kinase 1
Identifiers
Symbol(s)	MAP4K1; HPK1
External IDs	OMIM: 601983 MGI: 1346882 HomoloGene: 5199
Gene ontology Molecular Function: • nucleotide binding • protein serine/threonine kinase activity • small GTPase regulator activity • protein binding • ATP binding • MAP kinase kinase kinase kinase activity • transferase activity Biological Process: • activation of MAPKKK activity • protein amino acid phosphorylation • response to stress • protein kinase cascade • activation of JNK activity • peptidyl-serine phosphorylation • regulation of hemocyte differentiation
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	11184	26411
Ensembl	ENSG00000104814	ENSMUSG00000037337
Uniprot	Q92918	Q3UJX3
Refseq	NM_001042600 (mRNA) NP_001036065 (protein)	NM_008279 (mRNA) NP_032305 (protein)
Location	Chr 19: 43.77 - 43.8 Mb	Chr 7: 28.69 - 28.71 Mb
Pubmed search	[1]	[2]

Mitogen-activated protein kinase kinase kinase kinase 1, also known as MAP4K1, is a human gene.